Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration.

Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration.

Pregnancy-associated malaria is a major health problem, which mainly affects primigravidae living in malaria endemic areas. The syndrome is precipitated by accumulation of infected erythrocytes in placental tissue through an interaction between chondroitin sulphate A on syncytiotrophoblasts and a pa...

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Main Authors: Madeleine Dahlbäck, Thomas S Rask, Pernille H Andersen, Morten A Nielsen, Nicaise T Ndam, Mafalda Resende, Louise Turner, Philippe Deloron, Lars Hviid, Ole Lund, Anders Gorm Pedersen, Thor G Theander, Ali Salanti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.0020124

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https://doi.org/10.1371/journal.ppat.0020124

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