Intracellular and Extracellular Redox Status and Free Radical Generation in Primary Immune Cells from Children with Autism

The modulation of the redox microenvironment is an important regulator of immune cell activation and proliferation. To investigate immune cell redox status in autism we quantified the intracellular glutathione redox couple (GSH/GSSG) in resting peripheral blood mononuclear cells (PBMCs), activated m...

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Bibliographic Details
Main Authors: Shannon Rose, Stepan Melnyk, Timothy A. Trusty, Oleksandra Pavliv, Lisa Seidel, Jingyun Li, Todd Nick, S. Jill James
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Autism Research and Treatment
Online Access:http://dx.doi.org/10.1155/2012/986519