Visualizing Association of the Retroviral Gag Protein with Unspliced Viral RNA in the Nucleus

Visualizing Association of the Retroviral Gag Protein with Unspliced Viral RNA in the Nucleus

Retroviruses cause severe diseases in animals and humans, including cancer and acquired immunodeficiency syndromes. To propagate infection, retroviruses assemble new virus particles that contain viral proteins and unspliced vRNA to use as gRNA. Despite the critical requirement for gRNA packaging, th...

Full description

Bibliographic Details
Main Authors: Rebecca J. Kaddis Maldonado, Breanna Rice, Eunice C. Chen, Kevin M. Tuffy, Estelle F. Chiari, Kelly M. Fahrbach, Thomas J. Hope, Leslie J. Parent
Format: Article
Language:English
Published: American Society for Microbiology 2020-04-01
Series:mBio
Subjects:
gag proteins
rna trafficking
rous sarcoma virus
genomic rna packaging
live cell imaging
nucleocytoplasmic trafficking
retrovirus assembly
Online Access:https://doi.org/10.1128/mBio.00524-20

Internet

https://doi.org/10.1128/mBio.00524-20

Similar Items