The effect of combined treatment with canagliflozin and teneligliptin on glucose intolerance in Zucker diabetic fatty rats

The effect of combined treatment with canagliflozin and teneligliptin on glucose intolerance in Zucker diabetic fatty rats

To assess the impact of concomitant inhibition of sodium-glucose cotransporter (SGLT) 2 and dipeptidyl peptidase IV (DPP4) for the treatment of type 2 diabetes mellitus (T2DM), the effect of combined treatment with canagliflozin, a novel SGLT2 inhibitor, and teneligliptin, a DPP4 inhibitor, on gluco...

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Bibliographic Details
Main Authors: Takahiro Oguma, Chiaki Kuriyama, Keiko Nakayama, Yasuaki Matsushita, Kumiko Yoshida, Satoko Kiuchi, Yuka Ikenaga, Yoshinobu Nakamaru, Kumiko Hikida, Akira Saito, Kenji Arakawa, Kozo Oka, Kiichiro Ueta, Masaharu Shiotani
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Journal of Pharmacological Sciences
Subjects:
Canagliflozin
Teneligliptin
Combination treatment
Glucagon-like peptide-1
Zucker diabetic fatty rats
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861315000687

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http://www.sciencedirect.com/science/article/pii/S1347861315000687

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