The role of Interleukin-12 in immune-mediated rheumatic diseases

Objective: IL-12 is a proinflammatory cytokine produced by different antigen presenting cells. It has been shown to exert a critical role in inducing Th1 phenotype, thus initiating cell-mediated immune responses, but the significance of IL-12 in rheumatic diseases is not clear. Aim of the study was...

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Bibliographic Details
Main Authors: A. Spadaro, R. Scrivo, T. Rinaldi, V. Riccieri, A. Sili Scavalli, E. Taccari, G. Valesini
Format: Article
Language:English
Published: PAGEPress Publications 2002-06-01
Series:Reumatismo
Online Access:https://reumatismo.org/index.php/reuma/article/view/65