Detection and utility of cell-free and circulating tumour DNA in bone and soft-tissue sarcomas

Detection and utility of cell-free and circulating tumour DNA in bone and soft-tissue sarcomas

Aims: Cell-free DNA (cfDNA) and circulating tumour DNA (ctDNA) are used for prognostication and monitoring in patients with carcinomas, but their utility is unclear in sarcomas. The objectives of this pilot study were to explore the prognostic significance of cfDNA and investigate whether tumour-spe...

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Bibliographic Details
Main Authors: Kim M. Tsoi, Nalan Gokgoz, Paige Darville-O'Quinn, Patrick Prochazka, Ainaz Malekoltojari, Anthony M. Griffin, Peter C. Ferguson, Jay S. Wunder, Irene L. Andrulis
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2021-09-01
Series:Bone & Joint Research
Subjects:
sarcoma
cell-free dna
circulating tumour dna
soft-tissue sarcomas
dnas
sarcomas
blood
biomarkers
carcinomas
polymerase chain reaction
cancers
chondrosarcoma
quantitative pcr
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.109.BJR-2021-0014.R1

Internet

https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.109.BJR-2021-0014.R1

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