A Top Down View of Tumor Microenvironment: Structure, Cells and Signalling

A Top Down View of Tumor Microenvironment: Structure, Cells and Signalling

It is well established that the tumour microenvironment contributes to cancer progression. Stromal cells can be divided into mesenchymal, vascular and immune. Signalling molecules secreted by the tumour corrupts these cells to create ‘activated’ stroma. Equally, the extracellular matrix contributes...

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Bibliographic Details
Main Authors: Rahul eBhome, Marc eBullock, Hajir eAl Saihati, Rebecca eGoh, John ePrimrose, A. Emre eSayan, Alexander eMirnezami
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Extracellular Matrix
MicroRNAs
Tumor Microenvironment
Cancer-associated fibroblast
Cancer stroma
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00033/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00033/full

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