Improvement of Radiotherapy-Induced Lacrimal Gland Injury by Induced Pluripotent Stem Cell-Derived Conditioned Medium via MDK and Inhibition of the p38/JNK Pathway

Improvement of Radiotherapy-Induced Lacrimal Gland Injury by Induced Pluripotent Stem Cell-Derived Conditioned Medium via MDK and Inhibition of the p38/JNK Pathway

Radiation therapy is the most widely used and effective treatment for orbital tumors, but it causes dry eye due to lacrimal gland damage. Induced pluripotent stem cell-derived conditioned medium (iPSC-CM) has been shown to rescue different types of tissue damage. The present study investigated the...

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Bibliographic Details
Main Authors: Yanqing Zhang, Chenliang Deng, Jiang Qian, Mingui Zhang, Xiaofeng Li
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:International Journal of Molecular Sciences
Subjects:
radiotherapy
P38
lacrimal gland
induced pluripotent stem cell
Online Access:http://www.mdpi.com/1422-0067/15/10/18407

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http://www.mdpi.com/1422-0067/15/10/18407

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