Drifter technique: a new method to obtain metaphases in Hep-2 cell line cultures

The Hep-2 cell line is derived from laryngeal carcinoma cells and is often utilized as a model in carcinogenesis and mutagenesis tests. To evaluate the proliferative potential of this line, we developed a cytogenetic methodology (drifter technique) to obtain metaphases from cells that loose cellular...

Full description

Bibliographic Details
Main Authors: Eleonidas Moura Lima, Jorge Dores Rissino, Adriana Costa Guimarães, David James Overal, André Salim Khayat, Patrícia Carvalho de Souza, Denise Maria Christofolini, Marília de Arruda Cardoso Smith, Rommel Rodríguez Burbano
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2005-07-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000500005