Mitochondrial efficiency and insulin resistance

Mitochondrial efficiency and insulin resistance

Insulin resistance, ‘a relative impairment in the ability of insulin to exert its effects on glucose,protein and lipid metabolism in target tissues’, has many detrimental effects on metabolism and is strongly correlated to deposition of lipids in non-adipose tissues. Mitochondria are the main cellu...

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Bibliographic Details
Main Authors: Raffaella eCrescenzo, Francesca eBianco, Arianna eMazzoli, Antonia eGiacco, Giovanna eLiverini, SUSANNA eIOSSA
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Physiology
Subjects:
Insulin
skeletal muscle
type 2 diabetes
proton leak
mitochondra
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00512/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00512/full

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