Histone acetylase inhibitor curcumin impairs mouse spermiogenesis-an in vitro study.

In the previous study, we unraveled the unique "erasure strategy" during the mouse spermiogenesis. Chromatin associated proteins sequentially disassociated from the spermatid chromosome, which led to the termination of transcription in elongating spermatids. By this process, a relatively n...

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Bibliographic Details
Main Authors: Xiaoyu Xia, Heng Cai, Shixiao Qin, Chen Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3492465?pdf=render