Transfusion of Resting Platelets Reduces Brain Hemorrhage After Intracerebral Hemorrhage and tPA-Induced Hemorrhage After Cerebral Ischemia

BackgroundExacerbated blood-brain barrier (BBB) damage is related with tissue plasminogen activator (tPA)-induced brain hemorrhage after stroke. Platelets have long been recognized as the cellular orchestrators of primary haemostasis. Recent studies have demonstrated further that platelets are requi...

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Bibliographic Details
Main Authors: Haiyu Luo, Lixiang Wei, Lu Lu, Lijing Kang, Yongliang Cao, Xing Yang, Xiaofei Bai, Wenying Fan, Bing-Qiao Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Neuroscience
Subjects:
tPA
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00338/full