Cough Reflex Induced by Microinjection of Citric Acid Into the Larynx of Guinea Pigs: New Coughing Model

ABSTRACT: We developed a new coughing model that evoked coughs by microinjection of citric acid into the larynx in unanesthetized unrestrained guinea pigs; additionally, we recorded synchronous sounds and waveforms of coughing utilizing built-in microphones and a whole body plethysmograph. The cough...

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Bibliographic Details
Main Authors: Motomu Tanaka, Kei Maruyama
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319325617