Aspirin Prevention of Colorectal Cancer: Focus on NF-κB Signalling and the Nucleolus

Aspirin Prevention of Colorectal Cancer: Focus on NF-κB Signalling and the Nucleolus

Overwhelming evidence indicates that aspirin and related non-steroidal anti-inflammatory drugs (NSAIDs) have anti-tumour activity and the potential to prevent cancer, particularly colorectal cancer. However, the mechanisms underlying this effect remain hypothetical. Dysregulation of the nuclear fact...

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Bibliographic Details
Main Authors: Jingyu Chen, Lesley A. Stark
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Biomedicines
Subjects:
Aspirin
non-steroidal anti-inflammatory drugs
nuclear factor kappaB
apoptosis
colon cancer
nucleolus
nucleolar
nucleoli
sequestration
stress
RelA
p65
Online Access:https://www.mdpi.com/2227-9059/5/3/43

Internet

https://www.mdpi.com/2227-9059/5/3/43

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