Hyperglycemia activates the renin-angiotensin system and induces epithelial-mesenchymal transition in streptozotocin-induced diabetic kidneys

Introduction: The renin–angiotensin system and epithelial–mesenchymal transition play crucial roles in the development of kidney fibrosis. The connection between the renin–angiotensin system and transforming growth factor-β in epithelial–mesenchymal transition remains largely unknown. Materials and...

Full description

Bibliographic Details
Main Authors: Chung-Ming Chen, Shu-Hui Juan, Hsiu-Chu Chou
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2018-09-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320318803009