Epithelial to Mesenchymal Transition Regulates Surface PD-L1 via CMTM6 and CMTM7 Induction in Breast Cancer

Epithelial to Mesenchymal Transition Regulates Surface PD-L1 via CMTM6 and CMTM7 Induction in Breast Cancer

CMTM6 is a critical regulator of cell surface expression of PD-L1 in tumor cells, but little is known about the transcriptional regulation of CMTM6. Here we report that the expression of CMTM6 positively correlates with the epithelial to mesenchymal transition (EMT) score in breast cancer cell lines...

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Bibliographic Details
Main Authors: Malina Xiao, Meriem Hasmim, Audrey Lequeux, Kris Van Moer, Tuan Zea Tan, Christine Gilles, Brett G. Hollier, Jean Paul Thiery, Guy Berchem, Bassam Janji, Muhammad Zaeem Noman
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
breast cancer
epithelial to mesenchymal transition
snail1
CMTM family
immune checkpoints
Online Access:https://www.mdpi.com/2072-6694/13/5/1165

Internet

https://www.mdpi.com/2072-6694/13/5/1165

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