Reproductive characteristics modify the association between global DNA methylation and breast cancer risk in a population-based sample of women.

DNA methylation has been implicated in breast cancer aetiology, but little is known about whether reproductive history and DNA methylation interact to influence carcinogenesis. This study examined modification of the association between global DNA methylation and breast cancer risk by reproductive c...

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Bibliographic Details
Main Authors: Lindsay J Collin, Lauren E McCullough, Kathleen Conway, Alexandra J White, Xinran Xu, Yoon Hee Cho, Sumitra Shantakumar, Susan L Teitelbaum, Alfred I Neugut, Regina M Santella, Jia Chen, Marilie D Gammon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0210884