Chamaejasmine B Induces the Anergy of Vascular Endothelial Cells to VEGFA Pro-angiogenic Signal by Autophagic Regulation of VEGFR2 in Breast Cancer

Chamaejasmine B Induces the Anergy of Vascular Endothelial Cells to VEGFA Pro-angiogenic Signal by Autophagic Regulation of VEGFR2 in Breast Cancer

The neovascularization functions essentially for malignant upgrading and predicts poor prognosis in multiple cancers, which make it the highly effective strategy for clinical treatment. Unfortunately, the known anti-angiogenic therapies show low effectiveness against breast cancer. Recently, rebalan...

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Bibliographic Details
Main Authors: Qi Li, Xiaoxi Kan, Jie Yin, Lidong Sun, Yajie Wang, Yujie Li, Qing Yang, Hongbin Xiao, Ying Chen, Xiaogang Weng, Weiyan Cai, Xiaoxin Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Pharmacology
Subjects:
Chamaejasmine B
anti-angiogenesis chemotherapy
breast cancer
autophagy
VEGFR2
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00963/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00963/full

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