Development and validation of a new analytical HPLC method for simultaneous determination of the antidiabetic drugs, metformin and gliclazide

An efficient and simple HPLC method has been developed and validated for the simultaneous determination of gliclazide and metformin hydrochloride in bulk and was applied on marketed metformin and gliclazide products. The mobile phase used for the chromatographic runs consisted of 20 mM ammonium form...

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Bibliographic Details
Main Authors: Ahmed Gedawy, Hani Al-Salami, Crispin R. Dass
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Journal of Food and Drug Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S1021949818301121