TBC-8, a putative RAB-2 GAP, regulates dense core vesicle maturation in Caenorhabditis elegans.

TBC-8, a putative RAB-2 GAP, regulates dense core vesicle maturation in Caenorhabditis elegans.

Dense core vesicles (DCVs) are thought to be generated at the late Golgi apparatus as immature DCVs, which subsequently undergo a maturation process through clathrin-mediated membrane remodeling events. This maturation process is required for efficient processing of neuropeptides within DCVs and for...

Full description

Bibliographic Details
Main Authors: Mandy Hannemann, Nikhil Sasidharan, Jan Hegermann, Lena M Kutscher, Sabine Koenig, Stefan Eimer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3359978?pdf=render

Internet

http://europepmc.org/articles/PMC3359978?pdf=render

Similar Items