BRAF Mutations and Dysregulation of the MAP Kinase Pathway Associated to Sinonasal Mucosal Melanomas

BRAF Mutations and Dysregulation of the MAP Kinase Pathway Associated to Sinonasal Mucosal Melanomas

Sinonasal mucosal melanoma (SNM) is a rare and aggressive type of melanoma, and because of this, we currently have a limited understanding of its genetic and molecular constitution. The incidence among SNMs of somatic mutations in the genes involved in the main molecular pathways, which have been la...

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Bibliographic Details
Main Authors: Maria Colombino, Panagiotis Paliogiannis, Antonio Cossu, Valli De Re, Gianmaria Miolo, Gerardo Botti, Giosuè Scognamiglio, Paolo Antonio Ascierto, Davide Adriano Santeufemia, Filippo Fraggetta, Antonella Manca, Maria Cristina Sini, Milena Casula, Grazia Palomba, Marina Pisano, Valentina Doneddu, Amelia Lissia, Maria Antonietta Fedeli, Giuseppe Palmieri
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Journal of Clinical Medicine
Subjects:
cancer pathogenesis
sinonasal mucosal melanoma
mutation screening
braf gene
mapk pathway
Online Access:https://www.mdpi.com/2077-0383/8/10/1577

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https://www.mdpi.com/2077-0383/8/10/1577

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