Design and Clinical Application of an Integrated Microfluidic Device for Circulating Tumor Cells Isolation and Single-Cell Analysis

Design and Clinical Application of an Integrated Microfluidic Device for Circulating Tumor Cells Isolation and Single-Cell Analysis

Circulating tumor cells (CTCs) have been considered as an alternative to tissue biopsy for providing both germline-specific and tumor-derived genetic variations. Single-cell analysis of CTCs enables in-depth investigation of tumor heterogeneity and individualized clinical assessment. However, common...

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Bibliographic Details
Main Authors: Mingxin Xu, Wenwen Liu, Kun Zou, Song Wei, Xinri Zhang, Encheng Li, Qi Wang
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Micromachines
Subjects:
CTC-isolation
microfluidics
single-cell analysis
high-throughput sequencing
lung cancer
Online Access:https://www.mdpi.com/2072-666X/12/1/49

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https://www.mdpi.com/2072-666X/12/1/49

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