Development of alveolar-capillary-exchange (ACE) chip and its application for assessment of PM2.5-induced toxicity

Although standard two-dimensional (2D) cell culture is an effective tool for cell studies, monolayer cultivation can yield imperfect or misleading information about numerous biological functions. In this study, we developed an alveolar-capillary exchange (ACE) chip aiming to simulate the cellular mi...

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Bibliographic Details
Main Authors: Mingyang Guan, Song Tang, Huiyun Chang, Yuanyuan Chen, Fengge Chen, Ying Mu, Dong Zhao, Weiwei Fan, Huifang Tian, Diane C. Darland, Ying Zhang
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651321007132