Structural insights into the substrate-binding proteins Mce1A and Mce4A from Mycobacterium tuberculosis

Structural insights into the substrate-binding proteins Mce1A and Mce4A from Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb), which is responsible for more than a million deaths annually, uses lipids as the source of carbon and energy for its survival in the latent phase of infection. Mtb cannot synthesize all of the lipid molecules required for its growth and pathogenicity. Therefore, it...

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Bibliographic Details
Main Authors: Pooja Asthana, Dhirendra Singh, Jan Skov Pedersen, Mikko J. Hynönen, Ramita Sulu, Abhinandan V. Murthy, Mikko Laitaoja, Janne Jänis, Lee W. Riley, Rajaram Venkatesan
Format: Article
Language:English
Published: International Union of Crystallography 2021-09-01
Series:IUCrJ
Subjects:
mycobacterium tuberculosis
mammalian cell entry proteins
mce1
mce4
substrate-binding proteins
lipids
abc transporters
crystal structure
saxs
membrane proteins
protein structure
x-ray crystallography
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2052252521006199

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http://scripts.iucr.org/cgi-bin/paper?S2052252521006199

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