Long noncoding RNA NEAT1 suppresses hepatocyte proliferation in fulminant hepatic failure through increased recruitment of EZH2 to the LATS2 promoter region and promotion of H3K27me3 methylation

Liver failure: A NEAT possibility for treatment A long noncoding RNA molecule, one that does not encode the synthesis of protein, is implicated in acute liver failure (AHF) and might offer a new target for drugs to treat the condition. AHF can be induced by various factors, including viruses, drugs,...

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Bibliographic Details
Main Authors: Qiang Wang, Lian Liu, Sheng Zhang, Yingzi Ming, Shu Liu, Ke Cheng, Yujun Zhao
Format: Article
Language:English
Published: Nature Publishing Group 2020-03-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-020-0387-z