Glomerular endothelial cell heterogeneity in Alport syndrome

Abstract Glomerular endothelial cells (GEC) are a crucial component of the glomerular physiology and their damage contributes to the progression of chronic kidney diseases. How GEC affect the pathology of Alport syndrome (AS) however, is unclear. We characterized GEC from wild type (WT) and col4α5 k...

Full description

Bibliographic Details
Main Authors: Hasmik Soloyan, Matthew Thornton, Valentina Villani, Patrick Khatchadourian, Paolo Cravedi, Andrea Angeletti, Brendan Grubbs, Roger De Filippo, Laura Perin, Sargis Sedrakyan
Format: Article
Language:English
Published: Nature Publishing Group 2020-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-67588-0