TNF-α-induced miR-155 regulates IL-6 signaling in rheumatoid synovial fibroblasts

TNF-α-induced miR-155 regulates IL-6 signaling in rheumatoid synovial fibroblasts

Abstract Background MicroRNAs (miRNAs) are important regulators of a variety of inflammatory mediators. The present study was undertaken to elucidate the role of miRNAs in the rheumatoid cytokine network. Methods We analyzed miRNA expression in rheumatoid synovial fibroblasts (RASFs). miRNA array-ba...

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Bibliographic Details
Main Authors: Kiyoshi Migita, Nozomi Iwanaga, Yasumori Izumi, Chieko Kawahara, Kenji Kumagai, Tadashi Nakamura, Tomohiro Koga, Atsushi Kawakami
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Research Notes
Subjects:
Cytokines
Interleukin-6
MicroRNAs
Rheumatoid arthritis
Synovial fibroblasts
Tumor necrosis factor-α
Online Access:http://link.springer.com/article/10.1186/s13104-017-2715-5

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http://link.springer.com/article/10.1186/s13104-017-2715-5

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