Renal effects of long-term darbepoetin alpha treatment in hypertensive TGR(mRen2)27 rats

Introduction : Erytropoietin (EPO) has cytoprotective and angiogenic properties and has a beneficial effect in ischaemic conditions. Since the development of renal interstitial abnormalities are often associated with ischaemia, we studied the effects of the long-acting EPO analogue darbepoetin alpha...

Full description

Bibliographic Details
Main Authors: Anne-Roos S Frenay, Willem-Peter T Ruifrok, Marian Bulthuis, Sippie Huitema, Rudolf A de Boer, Harry van Goor
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2012-06-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320311432186