Inhibiting Basal Ganglia Regions Reduces Syllable Sequencing Errors in Parkinson's Disease: A Computer Simulation Study

Inhibiting Basal Ganglia Regions Reduces Syllable Sequencing Errors in Parkinson's Disease: A Computer Simulation Study

Background: Parkinson's disease affects many motor processes including speech. Besides drug treatment, deep brain stimulation (DBS) in the subthalamic nucleus (STN) and globus pallidus internus (GPi) has developed as an effective therapy.Goal: We present a neural model that simulates a syllable...

Full description

Bibliographic Details
Main Authors: Valentin Senft, Terrence C. Stewart, Trevor Bekolay, Chris Eliasmith, Bernd J. Kröger
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Computational Neuroscience
Subjects:
deep brain stimulation
basal ganglia
neural engineering framework
Parkinson's disease
speech
speech disorders
Online Access:https://www.frontiersin.org/article/10.3389/fncom.2018.00041/full

Internet

https://www.frontiersin.org/article/10.3389/fncom.2018.00041/full

Similar Items