Effects of aliskiren on stroke in rats expressing human renin and angiotensinogen genes.

<h4>Objective</h4>Pre-treatment with angiotensin receptor blockers is known to improve neurological outcome after stroke. This study investigated for the first time, whether the renin inhibitor aliskiren has similar neuroprotective effects.<h4>Methods</h4>Since aliskiren spec...

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Bibliographic Details
Main Authors: Kristin Schmerbach, Thiemo Pfab, Yi Zhao, Juraj Culman, Susanne Mueller, Arno Villringer, Dominik N Muller, Berthold Hocher, Thomas Unger, Christa Thoene-Reineke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21124781/?tool=EBI