High mitochondrial calcium levels precede neuronal death in vivo in Alzheimer’s disease

Alzheimer’s disease (AD), the most common cause of dementia, affects millions of people worldwide. Suggested mechanisms of neurotoxicity in AD include impaired calcium (Ca2+) homeostasis and mitochondrial dysfunction, both contributing to neuronal damage. Little was known about the exact mitochondri...

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Bibliographic Details
Main Authors: Maria Calvo-Rodriguez, Brian J. Bacskai
Format: Article
Language:English
Published: Shared Science Publishers OG 2020-06-01
Series:Cell Stress
Subjects:
Online Access:http://www.cell-stress.com/researcharticles/2020a-calvo-rodriguez-cell-stress/