The Non-Essential Mycolic Acid Biosynthesis Genes hadA and hadC Contribute to the Physiology and Fitness of Mycobacterium smegmatis.

The Non-Essential Mycolic Acid Biosynthesis Genes hadA and hadC Contribute to the Physiology and Fitness of Mycobacterium smegmatis.

Gram positive mycobacteria with a high GC content, such as the etiological agent of tuberculosis Mycobacterium tuberculosis, possess an outer membrane mainly composed of mycolic acids (MAs), the so-called mycomembrane, which is essential for the cell. About thirty genes are involved in the biosynthe...

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Bibliographic Details
Main Authors: Stevie Jamet, Nawel Slama, Joana Domingues, Françoise Laval, Pauline Texier, Nathalie Eynard, Annaik Quémard, Antonio Peixoto, Anne Lemassu, Mamadou Daffé, Kaymeuang Cam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4689354?pdf=render

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http://europepmc.org/articles/PMC4689354?pdf=render

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