RNA Dependent RNA Polymerases: Insights from Structure, Function and Evolution

RNA dependent RNA polymerase (RdRp) is one of the most versatile enzymes of RNA viruses that is indispensable for replicating the genome as well as for carrying out transcription. The core structural features of RdRps are conserved, despite the divergence in their sequences. The structure of RdRp re...

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Bibliographic Details
Main Authors: Sangita Venkataraman, Burra V. L. S. Prasad, Ramasamy Selvarajan
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/10/2/76