Senescence-Inflammatory Regulation of Reparative Cellular Reprogramming in Aging and Cancer
The inability of adult tissues to transitorily generate cells with functional stem cell-like properties is a major obstacle to tissue self-repair. Nuclear reprogramming-like phenomena that induce a transient acquisition of epigenetic plasticity and phenotype malleability may constitute a reparative...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-05-01
|
Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fcell.2017.00049/full |