MELK promotes Endometrial carcinoma progression via activating mTOR signaling pathway

Background: Endometrial carcinoma (EC) is one of the most common gynecological malignancies among women. Maternal embryonic leucine Zipper Kinase (MELK) is upregulated in a variety of human tumors, where it contributes to malignant phenotype and correlates with a poor prognosis. However, the biologi...

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Bibliographic Details
Main Authors: Qinyang Xu, Qiulin Ge, Yang Zhou, Bikang Yang, Qin Yang, Shuheng Jiang, Rongzhen Jiang, Zhihong Ai, Zhigang Zhang, Yincheng Teng
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419308242