Protein Adsorption Hysteresis and Transient States of Fibrinogen and BMP-2 as Model Mechanisms for Proteome-Binding to Implants

Protein Adsorption Hysteresis and Transient States of Fibrinogen and BMP-2 as Model Mechanisms for Proteome-Binding to Implants

Protein adsorption studies returned to the focus of medical therapeutics, when it was found that up to 2500 non-plasma proteins adsorbed to hip implants during arthroplastic surgery, challenging peri-implant healing models. Questions have re-emerged as to the implications of uncontrolled protein unf...

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Bibliographic Details
Main Authors: Jennissen H. P, Dohle Daniel S., Zmbrink Thomas, Meißner Michael
Format: Article
Language:English
Published: De Gruyter 2020-09-01
Series:Current Directions in Biomedical Engineering
Subjects:
adsorption and desorption isotherms
total internal reflection fluorescence (tirf)
tirf-rheometry
binding constants
hill constants
on-rate (k+1)
off-rate (k-1)
Online Access:https://doi.org/10.1515/cdbme-2020-3046

Internet

https://doi.org/10.1515/cdbme-2020-3046

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