LDL-Cholesterol Increases the Transcytosis of Molecules through Endothelial Monolayers.

Cholesterol has been identified as a causative factor in numerous pathologies including atherosclerosis and cancer. One of the frequent effects of elevated cholesterol levels in humans is the compromise of endothelial function due to activation of pro-inflammatory signalling pathways. While the mech...

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Bibliographic Details
Main Authors: Ana Magalhaes, Inês Matias, Inês Palmela, Maria Alexandra Brito, Sérgio Dias
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5047627?pdf=render