Investigating RNA expression profiles altered by nicotinamide mononucleotide therapy in a chronic model of alcoholic liver disease

Investigating RNA expression profiles altered by nicotinamide mononucleotide therapy in a chronic model of alcoholic liver disease

Abstract Background Chronic alcohol consumption is a significant cause of liver disease worldwide. Several biochemical mechanisms have been linked to the initiation and progression of alcoholic liver disease (ALD) such as oxidative stress, inflammation, and metabolic dysregulation, including the dis...

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Bibliographic Details
Main Authors: Mohammed A. Assiri, Hadi R. Ali, John O. Marentette, Youngho Yun, Juan Liu, Matthew D. Hirschey, Laura M. Saba, Peter S. Harris, Kristofer S. Fritz
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Human Genomics
Subjects:
Alcoholic liver disease
RNA-seq
Liver
NMN
ATF3
ERK1/2
Online Access:https://doi.org/10.1186/s40246-019-0251-1

Internet

https://doi.org/10.1186/s40246-019-0251-1

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