Cardioprotective Effect of Echinatin Against Ischemia/Reperfusion Injury: Involvement of Hippo/Yes-Associated Protein Signaling

Cardioprotective Effect of Echinatin Against Ischemia/Reperfusion Injury: Involvement of Hippo/Yes-Associated Protein Signaling

Background: Echinatin (Ech) has been reported to exert antioxidant and anti-inflammatory activities. In this study, we aimed to characterize the functional role of Ech in myocardial ischemic/reperfusion (MI/R) injury and elucidate its underlying mechanism of action.Method: We established in vivo and...

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Bibliographic Details
Main Authors: Jieting Niu, Yanguang Li, Xiang Song, Yunfeng Liu, Ying Li, Ya Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
echinatin
myocardial ischemia/reperfusion injury
hippo/yes kinase-associated protein signaling
caspase-3
lactate dehydrogenase
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.593225/full

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https://www.frontiersin.org/articles/10.3389/fphar.2020.593225/full

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