Long Noncoding RNA HITTERS Protects Oral Squamous Cell Carcinoma Cells from Endoplasmic Reticulum Stress‐Induced Apoptosis via Promoting MRE11‐RAD50‐NBS1 Complex Formation

Long Noncoding RNA HITTERS Protects Oral Squamous Cell Carcinoma Cells from Endoplasmic Reticulum Stress‐Induced Apoptosis via Promoting MRE11‐RAD50‐NBS1 Complex Formation

Abstract Recent studies have proven that long noncoding RNAs (lncRNAs) exhibit regulatory functions of both DNA damage response (DDR) and endoplasmic reticulum (ER) stress. Herein, ER stress‐induced lncRNA transcriptomic changes are reported in human oral squamous cell carcinoma (OSCC) cells and a n...

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Bibliographic Details
Main Authors: Chenzhou Wu, Wen Chen, Fanyuan Yu, Yihang Yuan, Yafei Chen, Douglas R. Hurst, Yi Li, Longjiang Li, Zhe Liu
Format: Article
Language:English
Published: Wiley 2020-11-01
Series:Advanced Science
Subjects:
apoptosis
DNA damage response
endoplasmic reticulum stress
long noncoding RNA
oral squamous cell carcinoma
Online Access:https://doi.org/10.1002/advs.202002747

Internet

https://doi.org/10.1002/advs.202002747

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