CRISPECTOR provides accurate estimation of genome editing translocation and off-target activity from comparative NGS data

CRISPECTOR provides accurate estimation of genome editing translocation and off-target activity from comparative NGS data

The control of off-target activity is a challenge for adapting CRISPR to therapeutic use. Here the authors present CRISPECTOR, a software tool to detect, evaluate and quantify editing activity, including translocations, from NGS data.

Bibliographic Details
Main Authors: Ido Amit, Ortal Iancu, Alona Levy-Jurgenson, Gavin Kurgan, Matthew S. McNeill, Garrett R. Rettig, Daniel Allen, Dor Breier, Nimrod Ben Haim, Yu Wang, Leon Anavy, Ayal Hendel, Zohar Yakhini
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22417-4

Internet

https://doi.org/10.1038/s41467-021-22417-4

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