A Similar Speciation Process Relying on Cellular Stochasticity in Microbial and Cancer Cell Populations

Summary: Similarities between microbial and cancer cells were noticed in recent years and serve as a basis for an atavism theory of cancer. Cancer cells would rely on the reactivation of an ancestral “genetic program” that would have been repressed in metazoan cells. Here we argue that cancer cells...

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Bibliographic Details
Main Authors: Jean-Pascal Capp, Frédéric Thomas
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220307239