Cytoskeletal influences on nuclear shape in granulocytic HL-60 cells

<p>Abstract</p> <p>Background</p> <p>During granulopoiesis in the bone marrow, the nucleus differentiates from ovoid to lobulated shape. Addition of retinoic acid (RA) to leukemic HL-60 cells induces development of lobulated nuclei, furnishing a convenient model system...

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Bibliographic Details
Main Authors: Olins Donald E, Olins Ada L
Format: Article
Language:English
Published: BMC 2004-08-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/5/30