Reduced subcutaneous adipogenesis in human hypertrophic obesity is linked to senescent precursor cells
Adipose tissue hypertrophy in obesity is associated with insulin resistance and other metabolic complications. Here, the authors analyze subcutaneous adipose tissue from patients with hypertrophic obesity and insulin resistance and find that adipocyte progenitor cells show features of senescence and...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-06-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-10688-x |