Optimizing a Human Papillomavirus Type 16 L1-Based Chimaeric Gene for Expression in Plants

Human papillomaviruses (HPVs) are the causative agents of cervical cancer, the fourth most prevalent cancer in women worldwide. The major capsid protein L1 self-assembles into virus-like particles (VLPs), even in the absence of the minor L2 protein: such VLPs have successfully been used as prophylac...

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Bibliographic Details
Main Authors: Inga I. Hitzeroth, Aleyo Chabeda, Mark P. Whitehead, Marcus Graf, Edward P. Rybicki
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
L1
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2018.00101/full