Evidence for liver and peripheral immune cells secreting tumor-suppressive extracellular vesicles in melanoma patients

Background: Before and after surgery melanoma patients harbor elevated levels of extracellular vesicles in plasma (pEV), suppressing tumor cell activity. However, due to technical reasons and lack of cell-specific biomarkers, their cellular origin remains obscure. Methods: We mimicked the interactio...

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Bibliographic Details
Main Authors: Jung-Hyun Lee, Martin Eberhardt, Katja Blume, Julio Vera, Andreas S. Baur
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420304953