Co-opted JNK/SAPK Signaling in Wnt/β-catenin–Induced Tumorigenesis

Aberrant stimulation of the canonical Wnt pathway induces mammary tumorigenesis in mice. It has been well documented that two types of tumors, adenocarcinoma and adenocarcinoma with squamous metaplasia, develop in these mutants. However, the molecular mechanism underlying the induction of squamous...

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Bibliographic Details
Main Authors: Bo Liu, Hsiao-Man Ivy Yu, Jiaoti Huang, Wei Hsu
Format: Article
Language:English
Published: Elsevier 2008-09-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558608801388