Co-opted JNK/SAPK Signaling in Wnt/β-catenin–Induced Tumorigenesis
Aberrant stimulation of the canonical Wnt pathway induces mammary tumorigenesis in mice. It has been well documented that two types of tumors, adenocarcinoma and adenocarcinoma with squamous metaplasia, develop in these mutants. However, the molecular mechanism underlying the induction of squamous...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2008-09-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558608801388 |