Therapeutic and prophylactic gastrectomy in a family with hereditary diffuse gastric cancer secondary to a CDH1 mutation: a case series

Therapeutic and prophylactic gastrectomy in a family with hereditary diffuse gastric cancer secondary to a CDH1 mutation: a case series

Abstract Background Gastric cancer is the fifth most prevalent and the third most lethal cancer worldwide, causing approximately 720,000 deaths annually. Although most cases of gastric cancers are sporadic, one of its inherited forms, hereditary diffuse gastric cancer (HDGC), constitutes about 1–3%...

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Bibliographic Details
Main Authors: Olsi Gjyshi, Pankaj Vashi, Laura Seewald, Mitra Kohan, Elham Abboud, Eric Fowler, Revathi Suppiah, Hatem Halabi
Format: Article
Language:English
Published: BMC 2018-07-01
Series:World Journal of Surgical Oncology
Subjects:
Hereditary diffuse gastric cancer (HDGC)
Cadherin-1 (CDH1)
Lobular breast cancer (LBC)
Online Access:http://link.springer.com/article/10.1186/s12957-018-1415-5

Internet

http://link.springer.com/article/10.1186/s12957-018-1415-5

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