Angiopoietin-Like 3 Induces Podocyte F-Actin Rearrangement through Integrin αVβ3/FAK/PI3K Pathway-Mediated Rac1 Activation

Angiopoietin-Like 3 Induces Podocyte F-Actin Rearrangement through Integrin αVβ3/FAK/PI3K Pathway-Mediated Rac1 Activation

Glomerular podocytes are highly differentiated cells whose foot processes, which are mainly maintained by the architecture of actin filaments, have a unique morphology. A rearrangement of F-actin in podocytes causes changes in their motility that involve foot process effacement and proteinuria in gl...

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Bibliographic Details
Main Authors:	Yi Lin, Jia Rao, Xi-liang Zha, Hong Xu
Format:	Article
Language:	English
Published:	Hindawi Limited 2013-01-01
Series:	BioMed Research International
Online Access:	http://dx.doi.org/10.1155/2013/135608

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