High‐fat diet induced obesity and age influence the telomere shelterin complex and telomerase gene expression in mouse adipose tissue

Abstract Obesity and aging are linked to inflammation and increased risk of chronic disease. Telomeres are the endcaps of chromosomes that are regulated by telomerase, the enzyme that elongates telomeres, as well as a protein complex known as shelterin. Telomere dysfunction is associated with inflam...

Full description

Bibliographic Details
Main Authors: Samuel I. Bloom, Andrei Tuluca, Stephen J. Ives, Thomas H. Reynolds
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.14461